I am quoting the manufacturer and this is not an endorsement since I haven’t tried one. Being a technut I am prone to seeing things techie and going, ooh! This line of keyboards and mice rate an OOH! Kids and in my case grandkids have a tendency to be a bit more destructive of computer peripherals than the normal user. Although I am sure gamers of all ages are probably the top of the destructive user food chain. From the Grandtec website: The Virtually Indestructible Mouse is a silicone-based optical mouse which features a unique combination of durability and comfort. The silicone-based material is impervious to most anything including water, coffee and cleaning solutions. Medical •Disinfect with either self-drying aerosols or cleanse with ammonia- or bleach-based medical grade disinfectants. •A study conducted by the Tripler Army Medical Center in Honolulu, Hawaii found that nearly 25 percent of the keyboards sampled harbored bacteria that is responsible for 95% of all hos...